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Sisodia, Sangram S.
One or more keywords matched the following items that are connected to Sisodia, Sangram S.
Item TypeName
Concept Tumor Cells, Cultured
Academic Article Evidence for phosphorylation and oligomeric assembly of presenilin 1.
Academic Article Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus.
Academic Article The profile of soluble amyloid beta protein in cultured cell media. Detection and quantification of amyloid beta protein and variants by immunoprecipitation-mass spectrometry.
Academic Article Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo.
Academic Article Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides.
Academic Article Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors.
Academic Article Endoproteolytic processing and stabilization of wild-type and mutant presenilin.
Academic Article Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia.
Academic Article Identification of the presenilins in hematopoietic cells with localization of presenilin 1 to neutrophil and platelet granules.
Academic Article Multiple effects of aspartate mutant presenilin 1 on the processing and trafficking of amyloid precursor protein.
Academic Article Familial Alzheimer disease-linked presenilin 1 variants enhance production of both Abeta 1-40 and Abeta 1-42 peptides that are only partially sensitive to a potent aspartyl protease transition state inhibitor of "gamma-secretase".
Academic Article Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein.
Academic Article Regulated hyperaccumulation of presenilin-1 and the "gamma-secretase" complex. Evidence for differential intramembranous processing of transmembrane subatrates.
Academic Article A role for presenilins in autophagy revisited: normal acidification of lysosomes in cells lacking PSEN1 and PSEN2.
Academic Article Stable association of presenilin derivatives and absence of presenilin interactions with APP.
Academic Article The topology of pen-2, a ?-secretase subunit, revisited: evidence for a reentrant loop and a single pass transmembrane domain.
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  • Tumor Cells Cultured